Genetic Analysis: An Integrated Approach, Global Edition

Series
Pearson
Author
Mark F. Sanders / John L. Bowman  
Publisher
Pearson
Cover
Softcover
Edition
2
Language
English
Total pages
892
Pub.-date
October 2015
ISBN13
9781292092362
ISBN
129209236X
Related Titles


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9781292092362
Genetic Analysis: An Integrated Approach, Global Edition
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Description

For all introductory genetics courses
Informed by many years of genetics teaching and research expertise, authors Mark Sanders and John Bowman use an integrated approach that helps contextualise three core challenges of learning genetics: solving problems, understanding evolution, and understanding the connection between traditional genetics models and more modern approaches.

Features

Develop Problem Solving Skills

  • Genetic Analysis worked examples provide unparalleled support for problem solving instruction. Each Genetic Analysis example guides students with a unique, consistent three-step approach that trains them to Evaluate, Deduce, and then Solve problems. Every Genetic Analysis example is presented in a clear, easy-to-follow, two-column format that helps students see the Solution Strategy in one column and its corresponding execution in the Solution Step.
  • NEW! “Break It Down” component has been added to each Genetic Analysis worked example to help students get started with formulating an approach to solving a problem. “Break It Down” models the concept of breaking down problem solving by deciphering the essential information stated in the problem.
  • End-of-Chapter Problems are divided into separate sections labeled Chapter Concepts and Application and Integration. The book offers a broad range of question types and level of difficulty. Answers to even-numbered problems appear in the Appendix.

Engage Students in the Process of Science and Genetic Discoveries

  • NEW! Integrated coverage of genomics throughout. Genomic investigations are rapidly expanding and changing what we know about genetics. Coverage of important techniques and findings are integrated throughout the text, such as a new discussion of the impact of lateral gene transfer on bacterial genomes in Chapter 6; a new Experimental Insight of cancer genomics in Chapter 12; discussions of new genome methods and analyses in Chapter 18; and updated coverage of the human genome, including data on interaction with Neandertals and Denisovans in Chapter 22.
  • NEW! Revised and expanded coverage of epigenetics in Chapters 11 and 15. Coverage in Chapter 15 has been substantially rewritten to expand the discussion of epigenetics, including new information on the histone code and chromatin states, and on epigenetic readers, writers, and erasers.
  • NEW! Expanded coverage of archaea molecular biology Recent advancements in understanding the genetics and molecular biology of archaea are described where appropriate. These recent findings allow insightful comparisons to the genetics of bacteria and eukaryotes, particularly in relation to molecular genetic processes and to evolution. New archaea discussions and descriptions appear in Chapters 7, 8, 9, 11, 12, and 14.
  • NEW! Enhanced coverage of molecular evolution The text’s focus on evolution in genetics now includes more coverage of molecular evolution integrated into appropriate chapters. Chapters 7, 8 and 9 have expanded discussions of the evolution of the processes of replication, transcription, and translation. Chapter 11 discusses the evolution of histone proteins in archaea and eukaryotes. Chapter 14 describes evolutionary comparisons of regulatory mechanisms in archaea and bacteria. Chapter 15 contains expanded coverage of the evolution of regulatory functions. Chapter 22 contains new discussions of evolution at the population, species, and molecular levels.
  • Experimental Insight essays discuss influential experiments, summarise real experimental data derived from the experiments, and explain conclusions drawn from the analysis of results.
  • Research Technique boxes explore important research methods and visually illustrate the results and interpretations of the techniques.
  • Unique Chapter 10: The Integration of Genetic Approaches integrates transmission genetics, molecular analysis, molecular techniques, and evolution in an exploration of human sickle cell disease.

New to this Edition

Develop Problem Solving Skills

  • NEW! Component has been added to each Genetic Analysis worked example to help students get started with formulating an approach to solving a problem.
  • End-of-Chapter Problems are divided into separate sections labeled Chapter Concepts and Application and Integration. The book offers a broad range of question types and level of difficulty. Answers to even-numbered problems appear in the Appendix.

Engage Students in the Process of Science and Genetic Discoveries

  • NEW! Integrated coverage of genomics throughout. Genomic investigations are rapidly expanding and changing what we know about genetics. Coverage of important techniques and findings are integrated throughout the text, such as a new discussion of the impact of lateral gene transfer on bacterial genomes in Chapter 6; a new Experimental Insight of cancer genomics in Chapter 12; discussions of new genome methods and analyses in Chapter 18; and updated coverage of the human genome, including data on interaction with Neandertals and Denisovans in Chapter 22.
  • NEW! Revised and expanded coverage of epigenetics in Chapters 11 and 15. Coverage in Chapter 15 has been substantially rewritten to expand the discussion of epigenetics, including new information on the histone code and chromatin states, and on epigenetic readers, writers, and erasers.
  • NEW! Expanded coverage of archaea molecular biology. Recent advancements in understanding the genetics and molecular biology of archaea are described where appropriate. These recent findings allow insightful comparisons to the genetics of bacteria and eukaryotes, particularly in relation to molecular genetic processes and to evolution. New archaea discussions and descriptions appear in Chapters 7, 8, 9, 11, 12, and 14.
  • NEW! Enhanced coverage of molecular evolution. The texts focus on evolution in genetics now includes more coverage of molecular evolution integrated into appropriate chapters. Chapters 7, 8 and 9 have expanded discussions of the evolution of the processes of replication, transcription, and translation. Chapter 11 discusses the evolution of histone proteins in archaea and eukaryotes. Chapter 14 describes evolutionary comparisons of regulatory mechanisms in archaea and bacteria. Chapter 15 contains expanded coverage of the evolution of regulatory functions. Chapter 22 contains new discussions of evolution at the population, species, and molecular levels.
  • Unique Chapter 10: The Integration of Genetic Approaches integrates transmission genetics, molecular analysis, molecular techniques, and evolution in an exploration of human sickle cell disease.

Help Students Distill the Most Important Take Home Lessons

  • NEW! Foundation Figures combine visuals and words to help students grasp pivotal genetics concepts in a concise, easy-to-follow format. Four new Foundation Figures have been added to this edition to help students understand DNA Replication (Chapter 7), Bacterial Transcription (Chapter 8), Bacterial Translation Elongation (Chapter 9) and the Molecular Model of Meiotic Recombination (Chapter 12).

MasteringGenetics is not included. Students, if MasteringGenetics is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN and course ID. MasteringGenetics should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.

Improve Results with MasteringGenetics

MasteringGenetics offers additional opportunities for students to master key concepts and practice problem-solving using interactive tutorials with hints and feedback. Instructors may also assign pre-lecture quizzes, end-of-chapter problems,

Table of Contents

  • 1 The Molecular Basis of Heredity, Variation, and Evolution
  • 2 Transmission Genetics
  • 3 Cell Division and Chromosome Heredity
  • 4 Inheritance Patterns of Single Genes and Gene Interaction
  • 5 Genetic Linkage and Mapping in Eukaryotes
  • 6 Genetic Analysis and Mapping in Bacteria and Bacteriophages
  • 7 DNA Structure and Replication
  • 8 Molecular Biology of Transcription and RNA Processing
  • 9 The Molecular Biology of Translation
  • 10   The Integration of Genetic Approaches: Understanding Sickle Cell Disease
  • 11   Chromosome Structure
  • 12   Gene Mutation, DNA Repair, and Homologous Recombination
  • 13   Chromosome Aberrations and Transposition
  • 14   Regulation of Gene Expression in Bacteria and Bacteriophage
  • 15   Regulation of Gene Expression in Eukaryotes
  • 16   Analysis of Gene Function via Forward Genetics and Reverse Genetics
  • 17   Recombinant DNA Technology and Its Applications
  • 18   Genomics: Genetics from a Whole-Genome Perspective
  • 19   Organelle Inheritance and the Evolution of Organelle Genomes
  • 20   Developmental Genetics
  • 21   Genetic Analysis of Quantitative Traits
  • 22   Population Genetics and Evolution at the Population, Species, and Molecular Levels
  • Selected References and Readings
  • Answers to Selected Problems
  • Glossary
  • Credits
  • Index  

Author

Mark F. Sanders has been a faculty member in the Department of Molecular and Cellular Biology at the University of California, Davis for 27 years. In that time, he has taught more than 120 genetics courses to more than 30,000 undergraduate students. Specializing in teaching the genetics course for which this book is written, Dr. Sanders also teaches a genetics laboratory course, an advanced human genetics course for biology majors, and a human heredity course for non-science majors. His teaching experience also includes introductory biology, and courses in population genetics and evolution.